James Woolley is a successful marketer who has several money-making sites in various niches. His latest site is a free internet marketing resource guide, which also includes a newsletter filled with free tips and bonuses.
http://www.jimsmarketing.com
Many webmasters spend a lot of time optimizing their home page only.
They do this by optimizing onpage factors like H1 tags, title, keyword density, alt tags, etc, and offpage factors like the number and quality of inward links from other sites. That's fine and is something you should definitely do, but you should also take some time to optimize all of your inner web pages as well.